An estimated 151,030 men and women will be diagnosed with colorectal cancer in 2022 and 52,580 individuals are estimated to die from the disease. Without a continued, dedicated federal investment in colorectal cancer prevention and early detection, the U.S. could experience a reduction in screening leading to increases in completely preventable colorectal cancer cases and deaths. This factsheet discusses the importance of continued funding for the Colorectal Cancer Control Program (CRCCP).